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Genoma PGD Lab
Genoma PGD Laboratory
About GENOMA PGD Lab
Our Mission
Our Research
Our Technologies
Our Expertise
Our Team
Our Founder
GENOMA Staff
ISO Accreditation
Worldwide services
Our Added Values
Why to choose Genoma Laboratory
Our experience in PGD
PGD for monogenic diseases
PGD for HLA Matching
PGD for Cancer
PGD for Late on-set Disorders
PGD for Aneuploidy screening
PGD for chromosomal translocations
PGD protocols available
How we work (Transport PGD)
Sending Samples
Guidelines for blastomeres collection and transportation
Preliminary PGD workup
Enrolling a Patient for PGD
Information on preliminary PGD workup
Development of PGD protocols
Patient Information form
Prescription for Drawing Blood
Blood / Buccal Swab Submission Form
Check list
Price List
Download info’s on PGD workup
PGD acceptance form
Services offered
PGD of aneuploidy
PGD of Translocations
PGD of Single Gene Defects
Genetic Counseling and patient information
Embryo biopsy and fixation services
Teaching at Genoma PGD Lab
International collaborations
Scientific Activity
Scientific News
Publications
International Talks
Press Release
Become a referring IVF Center
Preimplantation Genetic Diagnosis
What is PGD
Indications for PGD
Recurrent Miscarriage & Infertility
Unsuccessful IVF Cycles (>2)
Unexplained Infertility
Advanced Maternal Age
Male Factor Infertility
History of Chromosomally Abnormal Child or Pregnancy
Family history of structural chromosomal condition
Family history of X-linked disease
Inherited genetic disorders
How PGD is performed
Ovulation induction
Oocyte aspiration
Fertilization and Embryo Culture
Polar body removal and/or blastomere biopsy
Diagnosis in blastomeres
Embryo transfer and implantation
Genetic diseases that can be diagnosed by PGD
PGD in Italy: 1PB Testing
PGD on polar bodies
Preconception genetic diagnosis
Technical description of the procedure
Mutation analysis
Limitations
Advantages
Ethical issues
PGD Conditions
PGD for single gene disorders
Monogenic diseases
History and Experience
Preliminary workup
Genetic Analysis
Mutation detection
Establishing a diagnosis
Monogenic diseases that can be diagnosed by PGD
Our experience in PGD for single gene disorders
Example of the strategy used
PGD for myotonic dystrophy
PGD for Congenital Adrenal Hyperplasia (CAH)
PGD for b-Thalassemia
PGD for Primary dystonia
PGD for Duchenne muscular dystrophy (DMD)
Issues Associated with PGD for Single Gene Disorder (SGD)
PGD for HLA matching
Indications for preimplantation HLA matching
Diseases Treated with Stem Cells Transplantation
Standard Therapies
Therapies in Clinical Trials
Experimental Treatments
Preimplantation HLA matching procedure
Preliminary Analyses
Informativity testing on couples
Preclinical work-up
Genetic Testing
Example of PGD for HLA matching
Example b-thalassaemia + HLA
Example Wiskott-Aldrich syndrome + HLA
Example Diamond-Blackfan anemia + HLA
Reliability of diagnosis
HLA Limitations
HLA Ethical considerations
Our experience in PGD for HLA matching
Accuracy of PGD for HLA matching
PGD for inherited predisposition to cancer
Inherited cancer susceptibility
High and Lower penetrance conditions
Options for affected families
PGD for inherited cancer
Ethical issues associated with PGD for inherited cancer
Protocol available for inherited predisposition to cancer
Our experience in PGD for cancer
PGD for late on-set disorders
Late on-set disorders
Treatment Value
Our experience in PGD for late on-set disorders
PGD for Aneuploidy Screening (PGD-AS)
Chromosome Aneuploidy
Risk of Aneuploidy and maternal age
PGD-AS Procedure
Establishing a diagnosis
Accuracy and Interpretations
24 chromosome PGS by Array-CGH
Advantages of PGD for Aneuploidy Screening
Issues associated with PGD
Our experience in PGD for Aneuploidy screening
PGD for Chromosome Translocation
Chromosome Translocation
PGD Procedure
Preliminary Analyses
Advantages of PGD for translocation
Issues associated with PGD for translocation
Our experience in PGD for chromosomal translocations
References
Phisician's resources
Preliminary PGD workup
Enrolling a Patient for PGD
Information on preliminary PGD workup
Development of PGD protocols
Patient Information form
Prescription for Drawing Blood
Blood / Buccal Swab Submission Form
Check list
Price List
Downloads for PGD workup
Brochures
On-line Reporting
Ask to the experts
Becoming A Referring Center
Patient's resources
How is PGD is carried out
Ovulation induction
Oocyte aspiration
Fertilization and Embryo Culture
Polar body removal and/or blastomere biopsy
Diagnosis in blastomeres